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Gel electrophoresis equipment and tips for smarter gel electrophoresis:

 The Breakthrough of high-speed electrophoresis without running buffer

  See User Feedback about the performance of buffer-less high speed electrophoresis:

The principle of the 6Mgel invention

The inventor of 6mgel recognized that water is the best and cheapest coolant. The electrical resistance of lab dd-water is 18MΩ, which means that dd-water is an excellent electrical insulator. By simply adding dd-water directly on top of the buffer-containing agarose gel, the desired effects are achieved: gels can be run much faster!  You can add a large volume of dd-water to dissipate heat so that a much higher voltage can be applied to drive faster migration of DNA molecules. Gel smiling is eliminated because the large volume of dd-water in direct contact with the gel maintains even heat distribution. Also, sharper banding occurs due to "stacking effects of dd-water in gel wells.

In 6Mgel, the V/cm in wells is elevated about 3-fold higher than in the gel body, which drives DNA 3 times faster in wells than in the gel body, resulting in sharper bands. Furthermore, consumption of running buffer can be reduced by 50-75%.

During the development of 6Mgel, more and more features were added, such as buffer-less high speed electrophoresis, lab-made precast gels for high-speed electrophoresis, and agarose-saving gel equipments. Go to 6mgel electrophoresis equipments for more information.

Liberty 120 gel equipment operation steps:

1. Select gel length, 48, 88, or 128mm to meet sample quantity and running distance requirement.

2. Pour agarose gel solution into gel tray, place combs into comb slots, and let the agarose gel to set.

3. Remove combs, add 350ml of dd-water on gel top and 200ml of 1x running buffer into buffer reservoir.

4. Load samples into sample wells. Well distance is multi-channel pipette compatible.

5. Run rapid gel electrophoresis at 220V DC for 6-10 minutes depending on your applications.

6. Take gel pictures on UV transilluminator.

Liberty 120 gel equipment quality features:

UV transparent bottom is built with specially enforced UV trasmitting acrylic for working under UV light without cause cracking or aging. Gel chamber is built with heavy gauge solid blocks of Plexiglass

Q: Why 6M gel electrophoresis equipment is irresistible ? 

A: It is clear if you know the feature of 6mgel equipment, Since 1994, 6Mgel invention has passed over 10 model versions. The name of the latest model tells how 6M gel electrophoresis equipments are differ from any other gel electrophoresis equipments.

Febe Features:

Faster Easier Bufferless Electrophoresis

Run high-speed electrophoresis in 6-minute with no running buffer.

Cast 20 gels at once and store them for a month without any wrapping.

Have your own precast gels ready anytime without paying high prices of commercial gels.

Straight banding technology eliminates gel-smiling problem.

Previous models of 6M gel equipments

Super gel electrophoresis, including super 120 and super 80.

Screener gel electrophoresis, including super 13.

Scooter gel electrophoresis, including scooter 100, scooter 60.

Liberty gel electrophoresis, including liberty 1, liberty 2, liberty 4.

Q gel electrophoresis

RAGE gel electrophoresis, including RGX100 RGX 60.

Why Biokeystone gel electrophoresis instrument is the best?

In agarose gel electrophoresis instrument, the instrument chamber holds liquid buffer, such as TAE buffer, TBE buffer, and mops buffer. An agarose gel plate is immersed under the conductive electrophoresis running buffer. The electrophoresis buffer conducts electric current two electrodes of the electrophoresis equipments. Sample molecules in the electric field migrate along a direction from negative to positive according to their charge and molecular size. After agarose gel electrophoresis process, the gel plate is removed from the electrophoresis equipment  to a UV illuminator for picturing. Sample molecules form distinguished bands in the agarose gel plate. 

The conductive electrophoresis buffer in the electrophoresis instrument, while conducting electric current to agarose gel plate, generates undesired heat during agarose gel electrophoresis, which limits agarose gel electrophoresis a slow process at low voltage.

Biokeystone invents water cooling agarose gel electrophoresis instrument, a unique agarose gel electrophoresis equipment with so many advantages together, and leads agarose gel electrophoresis industry to modern generation.

High speed gel straight banding in 6 minutes

How to run precast gel electrophoresis instrument using no running buffer?

How to screening 96 PCR samples in 6 minute with Febe electrophoresis instrument?

Agarose gel electrophoresis instruments

How to run electrophoresis using no running buffer?

How to run electrophoresis application on 96 PCR samples in 6 minute?

  MCI: Microfluid Culture Insert

Generating robust cell cultures and co-cultures easily. Especially powerful for primary cell cultures and co-cultures. PLL/collagen coated, optically clear, sterile, ready to use... 

Liberty 120 high- speed gel instrument

Most attractive features:

One gel tray for 3 gel lengths to save agarose. You can reduce gel length from 128mm to 48mm whenever short electrophoresis is enough to see your genotyping PCR bands.

High-speed electrophoresis in only 6 minutes.

Straight banding -- Gel smiling has been eliminated (read more about gel smiling)

Buffer saving -- Only 200ml running buffer.

Rapid Mouse genotyping instrument

Genotyping is a basic daily operation in laboratories. Improvement of a single step makes a big difference to the result and speed of your projects. High quality fast genotyping gives you extra time to design your next experiment carefully.

Researchers are using Liberty 120 rapid genotyping PCR gel system together with the kit to optimize their work efficiency.

Why agarose-saving feature is so important for genotyping and PCR applications?

In agarose electrophoresis, the gel concentration is determined by the size range of the DNA /RNA fragments. Much higher percentage gel should be used to resolve small sizes, such as 100-200bps. For PCR genotyping reliability, most genotyping primers were designed to generate PCR products in small sizes range, which means that your agarose gel should be made to 3% or higher. 

Have you thought about how much is your cost to run a large agarose gel for only a few samples?

$368 / 500g biotech grade Agarose

See Genotyping / PCR results in 6 minutes

Agarose-saving high-speed gel electrophoresis

Most recognized 6Mgel instruments

Liberty 120

RGX 100

Liberty 1

Febe